Personal Narrative Of Travels To The Equinoctial Regions Of America During The Years 1799-1804 - Volume 1 - By Alexander Von Humboldt And Aime Bonpland.
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Of The Tulip-Tree
And The Quassia, It Is The Bark Of The Roots That Is Used.
Eminent
febrifuge virtues have also been found in the cortical part of the
roots of the Cinchona condaminea at Loxa; but it is fortunate, for
the preservation of the species, that the roots of the real
cinchona are not employed in pharmacy.
Chemical researches are yet
wanting upon the very powerful bitters contained in the roots of
the Zanthoriza apiifolia, and the Actaea racemosa: the latter have
sometimes been employed with success as a remedy against the
epidemic yellow fever in New York.) Some of these barks so much
resemble each other, that it is not easy to distinguish them at
first sight. But before we examine the question, whether we shall
one day discover, in the real cinchona, in the cuspa of Cumana, the
Cortex Angosturae, the Indian swietenia, the willows of Europe, the
berries of the coffee-tree and uvaria, a matter uniformly diffused,
and exhibiting (like starch, caoutchouc, and camphor) the same
chemical properties in different plants, we may ask whether, in the
present state of physiology and medicine, a febrifuge principle
ought to be admitted. Is it not probable, that the particular
derangement in the organization, known under the vague name of the
febrile state, and in which both the vascular and the nervous
systems are at the same time attacked, yields to remedies which do
not operate by the same principle, by the same mode of action on
the same organs, by the same play of chemical and electrical
attractions? We shall here confine ourselves to this observation,
that, in the species of the genus cinchona, the antifebrile virtues
do not appear to belong to the tannin (which is only accidentally
mingled in them), or to the cinchonate of lime; but in a resiniform
matter, soluble both by alcohol and by water, and which, it is
believed, is composed of two principles, the cinchonic bitter and
the cinchonic red.* (* In French, l'amer et le rouge cinchoniques.)
May it then be admitted, that this resiniform matter, which
possesses different degrees of energy according to the combinations
by which it is modified, is found in all febrifuge substances?
Those by which the sulphate of iron is precipitated of a green
colour, like the real cinchona, the bark of the white willow, and
the horned perisperm of the coffee-tree, do not on this account
denote identity of chemical composition;* and that identity might
even exist, without our concluding that the medical virtues were
analogous. (* The cuspare bark (Cort. Angosturae) yields with iron
a yellow precipitate; yet it is employed on the banks of the
Orinoco, and particularly at the town of St. Thomas of Angostura,
as an excellent cinchona; and on the other hand, the bark of the
common cherry tree, which has scarcely any febrifuge quality,
yields a green precipitate like the real cinchonas. Notwithstanding
the extreme imperfection of vegetable chemistry, the experiments
already made on cinchonas sufficiently show, that to judge of the
febrifuge virtues of a bark, we must not attach too much importance
either to the principle which turns to green the oxides of iron, or
to the tannin, or to the matter which precipitates infusions of
tan.) We see that specimens of sugar and tannin extracted from
plants, not of the same family, present numerous differences:
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