The Following Is The Series Of Pathological Facts, Considered In Their Simplest Point Of View.

When a great number of persons, born in a cold climate, arrive at the same period in a port of the torrid zone, not particularly dreaded by navigators, the typhus of America begins to appear.

Those persons have not had typhus during their passage; it appears among them only after they have landed. Is the atmospheric constitution changed? or is it that a new form of disease develops itself among individuals whose susceptibility is highly increased?

The typhus soon begins to extend its ravages among other Europeans, born in more southern countries. If propagated by contagion, it seems surprising that in the towns of the equinoctial continent it does not attach itself to certain streets; and that immediate contact* does not augment the danger, any more than seclusion diminishes it. (* In the oriental plague (another form of typhus characterised by great disorder of the lymphatic system) immediate contact is less to be feared than is generally thought. Larrey maintains that the tumified glands may be touched or cauterized without danger; but he thinks we ought not to risk putting on the clothes of persons attacked with the plague. - Memoire sur les Maladies de l'Armee Francoise en Egypte page 35.) The sick, when removed to the inland country, and especially to cooler and more elevated spots, to Xalapa, for instance, do not communicate typhus to the inhabitants of those places, either because the disease is not contagious in its nature, or because the predisposing causes are not the same as in the regions of the shore. When there is a considerable lowering of the temperature, the epidemic usually ceases, even on the spot where it first appeared. It again breaks out at the approach of the hot season, and sometimes long before; though during several months there may have been no sick person in the harbour, and no ship may have entered it.

The typhus of America appears to be confined to the shore, either because persons who bring the disease disembark there, and goods supposed to be impregnated with deleterious miasms are there accumulated; or because on the sea-side gaseous emanations of a particular nature are formed. The aspect of the places subject to the ravages of typhus seems often to exclude all idea of a local or endemical origin. It has been known to prevail in the Canaries, the Bermudas, and among the small West India Islands, in dry places formerly distinguished for the great salubrity of their climate. Examples of the propagation of the yellow fever in the inland parts of the torrid zone appear very doubtful: that malady may have been confounded with remitting bilious fevers. With respect to the temperate zone, in which the contagious character of the American typhus is more decided, the disease has unquestionably spread far from the shore, even into very elevated places, exposed to cool and dry winds, as in Spain at Medina-Sidonia, at Carlotta, and in the city of Murcia. That variety of phenomena which the same epidemic exhibits, according to the difference of climate, the union of predisposing causes, its shorter or longer duration, and the degree of its exacerbation, should render us extremely circumspect in tracing the secret causes of the American typhus. M. Bailly, who, at the time of the violent epidemics in 1802 and 1803, was chief physician to the colony of St. Domingo, and who studied that disease in the island of Cuba, the United States, and Spain, is of opinion that the typhus is very often, but not always, contagious.

Since the yellow fever has made such ravages in La Guayra, exaggerated accounts have been given of the uncleanliness in that little town as well as of Vera Cruz, and of the quays or wharfs of Philadelphia. In a place where the soil is extremely dry, destitute of vegetation, and where scarcely a few drops of water fall in the course of seven or eight months, the causes that produce what are called miasms, cannot be of very frequent occurrence. La Guayra appeared to me in general to be tolerably clean, with the exception of the quarter of the slaughter-houses. The sea-side has no beach on which the remains of fuci or molluscs are heaped up; but the neighbouring coast, which stretches eastward towards Cape Codera, and consequently to the windward of La Guayra, is extremely unhealthy. Intermitting, putrid, and bilious fevers often prevail at Macuto and at Caravalleda; and when from time to time the breeze is interrupted by a westerly wind, the little bay of Cotia sends air loaded with putrid emanations towards the coast of La Guayra, notwithstanding the rampart opposed by Cabo Blanco.

The irritability of the organs being so different in the people of the north and those of the south, it cannot be doubted, that with greater freedom of commerce, and more frequent and intimate communication between countries situated in different climates, the yellow fever will extend its ravages in the New World. It is even probable that the concurrence of so many exciting causes, and their action on individuals so differently organized, may give birth to new forms of disease and new deviations of the vital powers. This is one of the evils that inevitably attend rising civilization.

The yellow fever and the black vomit cease periodically at the Havannah and Vera Cruz, when the north winds bring the cold air of Canada towards the gulf of Mexico. But from the extreme equality of temperature which characterizes the climates of Porto Cabello, La Guayra, New Barcelona, and Cumana, it may be feared that the typhus will there become permanent, whenever, from a great influx of strangers, it has acquired a high degree of exacerbation.

Tracing the granitic coast of La Guayra westward, we find between that port (which is in fact but an ill-sheltered roadstead) and that of Porto Cabello, several indentations of the land, furnishing excellent anchorage for ships.

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